Volume: 36 Issue: 3
Standardization of drying and extraction techniques for better colchicine recovery from Gloriosa superba
Year: 2014, Page: 87-90, Doi: https://doi.org/10.62029/jmaps.v36i3.Keshore
Received: Aug. 8, 2014 Accepted: Nov. 20, 2014 Published: Dec. 31, 2014
Gloriosa superba is an important medicinal plant that is used in the treatment of diseases like gout, arthritis, cancer and act as anthelmintic, antimitotic and antiabortive agent. It’s tuber is a major source of colchicine for the pharmaceutical industries and requires drying before extraction. The accelerated artificial drying technique using microwave vacuum oven was evaluated with other methods of extraction & purification for colchicine by performing High Performance Liquid Chromatography (HPLC). It was observed that the recovery of colchicine from extracts prepared by Soxhlet method were greater than that of sonication. Likewise, colchicine content in extract of microwave vacuum dried tuber was greater as compared to the hot air oven dried tuber. This study is useful for pharmaceutical industries for extracting colchicine using accelerated drying techniques economically and in less time consuming manner.
Keywords: Colchicine, Gloriosa superb, HPLC, Microwave extraction
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© Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow (India)
Vineet Keshore, A D Rane, Gaurav Gupta, SS Narkhede, Vinod Singh Gour. 2014. Standardization of drying and extraction techniques for better colchicine recovery from Gloriosa superba. J Med Aromat Plant Sci 36: 87-90.
