Volume: 35 Issue: 3
Green synthesis of silver nanoparticles of bio-active phytochemicals with anti-bacterial activity from callus cultures of bitter gourd, Momordica charantia L.
Year: 2013, Page: 147-153, Doi: https://doi.org/10.62029/jmaps.v35i3.Iyer
Received: Oct. 26, 2013 Accepted: Dec. 20, 2013 Published: Dec. 31, 2013
Momordica charantia (bitter gourd), an anti-diabetic plant species, is a rich source of several bioactive molecules. In the present study the callus cultures of M. charantia were established in vitro and the presence of therapeutic compounds including lignans was detected in them. Rapid synthesis of silver nanoparticles by such calli was achieved. These nanoparticles as well as the ethanolic extract of the callus cultures exhibited strong anti-bacterial activity against methicillin-resistant Staphylococcus aureus. In addition the silver nanoparticles were also found active against drug-resistant strains of Pseudomonas aeruginosa. This is the first report of synthesis of silver nanoparticles from callus cultures of Momordica charantia.
Keywords: Callus, Drug resistant microbes, Momordica charantia, Silver nanoparticles
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© Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), Lucknow (India)
R Indira Iyer, H Sowmya, R Pooja Yashwanthi, C Selvaraju, ST Santhiya. 2013. Green synthesis of silver nanoparticles of bio-active phytochemicals with anti-bacterial activity from callus cultures of bitter gourd, Momordica charantia L. J Med Aromat Plant Sci 35: 147-153.
