Volume: 37 Issue: 1
Biotransformation of terpenoids by fungi and bacteria - A literature update
Year: 2015, Page: 1-17, Doi: https://doi.org/10.62029/jmaps.v37i1.Sethi
Received: Nov. 22, 2014 Accepted: June 30, 2015 Published: Dec. 31, 2015
Terpenenoids, which are naturally occurring organic compounds of plant and animal origin are presently gaining lot of scientific attention as potent antimicrobial agents. Monoterpenoids in plants have great ecological roles in acting as deterrents against feedings by herbivores, in defences against pathogens and as attractants for pollination. Sesquiterpenoids are also known to possess antibacterial properties with significant, pharmacological and clinical efficiency. Diterpenoids are also known to possess potent pharmacological activities. Several phytoextracts contain biologically active triterpenes which are found to possess anti-inflammatory, virostatic, hepatoprotective and antimycotic effects. Microbial transformation of terpenoids is being extensively studied to produce new metabolites with enhanced biological activity. The regio and stereo selective introduction of functional groups at unactivated carbon atom is achieved by biotransformation which is otherwise difficult with chemical methods. These terpenes and their derivatives can be utilized as chiral synthons for asymmetric synthesis. In present review we focus on the biotransformation of the various class of terpenoids by fungi and bacteria to obtain bioactive compounds from precursor torpene skeletons.
Keywords: Bacteria, Biotransformation, Fungi, Terpenes
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Sonali Sethi, OM Prakash, AK Pant. 2015. Biotransformation of terpenoids by fungi and bacteria - A literature update. J Med Aromat Plant Sci 37: 1-17.
